
About
Conversations with the best investors and business leaders in the world. Patrick explores their ideas, methods, and stories to help you better invest your time and money.

Patrick is the Founder and CEO of Positive Sum. He founded Colossus in 2020 to build on the success of Invest Like The Best.
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Invest Like The Best
Ep.355
A Conversation with Charlie Munger & John Collison
Charlie Munger was the vice chairman of Berkshire Hathaway. In this conversation with Stripe's John Collison, recorded last year, he shares the ingredients for long-term business success, his thoughts on American society writ large, and what makes Berkshire special.
12.05.2023

Invest Like The Best
Ep.427
The Gift and The Curse of Staying Private
Bill Gurley is a former General Partner at Benchmark Capital. We cover the breakdown of incentives that created over a thousand "zombie unicorn" companies, how late-stage venture firms have largely eliminated the need to go public to access funding and liquidity, and the investing implications if AI turns out to be the single greatest platform shift of our lifetime.
06.10.2025

Invest Like The Best
Ep.414
Investing At Lone Pine
Kelly Granat is the co-CIO and Managing Director of Lone Pine Capital. We cover the building blocks behind Lone Pine's investment decisions, why the market frequently misprices the ability to execute, and the investing industry's problems with aligning incentives and duration.
03.11.2025

Invest Like The Best
Ep.241
Building a Great Endowment
Scott Malpass was the CIO of Notre Dame's endowment for 32 years, building it into a powerhouse of the endowment world. We cover the qualities he looks for in great investors, how he recruited top talent to work at Notre Dame’s endowment, and how asset classes have evolved over his 30 years of investing,
08.31.2021

Invest Like The Best
Ep.240
Investing at the Supercritical Stage
Renata Quintini and Roseanne Wincek are co-founders and managing directors of Renegade Partners. We cover their investing philosophies, what it means to invest at the “supercritical stage” in venture, and what worries them most in search of businesses with outsized potential returns.
08.24.2021

Invest Like The Best
Ep.239
Exploring the Creative Process
Suzanne Ciani is a 5-time Grammy-nominated composer. We cover what it means to be an artist, how to evolve away from the need for approval and validation, and the importance of mentors during the creative process.
08.16.2021

Invest Like The Best
Ep.238
The Past, Present, and Future of Search
Sridhar Ramaswamy is the co-founder and CEO of Neeva, and Venture Partner at Greylock. We cover the history of search and what led to Google’s dominance, his view on the potential end-state for ad-based search engines, and how all of his experiences led him to found Neeva.
08.10.2021

Invest Like The Best
Ep.237
All Things Macro
Karen Karniol-Tambour is the Co-CIO for Sustainability at Bridgewater Associates. We cover a variety of the most important themes in the market today, how each of them has become more important for investors, and what today's 60/40 portfolio might look like.
08.03.2021

Invest Like The Best
Ep.236
Wisdom from Decades of Investing
Carl Kawaja is a long-time portfolio manager at Capital Group. We cover Carl’s criteria for building conviction around long-term holdings, his views on uncertainty, and his belief that failure is key to a great investing career.
07.27.2021

Invest Like The Best
Ep.235
Investing Behind Change
Steve Mandel is the founder of Lone Pine Capital, one of the most successful hedge fund and investment firms of this generation. We cover how the investing business has evolved since Steve started in the 1980s, why it’s so difficult to drive alpha by shorting stocks today, and why Steve still loves to get into the guts of a business.
07.20.2021

Invest Like The Best
Ep.234
How to Operate a SaaS Startup
David Sacks is a General Partner at Craft Ventures and founding COO of PayPal. We cover the ways in which operating cadence applies within an organization, what makes for a magical product launch event, and what key growth metrics David uses to measure success.
07.12.2021

Invest Like The Best
Ep.233
Optimizing Your Inputs
Balaji Srinivasan is a serial entrepreneur and angel investor. We cover ways to optimize your information diet, how technology is driving decentralisation, and what that could mean for countries, corporations, and individuals.
07.06.2021

Invest Like The Best
Ep.232
Making the Future
Marc Andreesen is a co-founder of Andreessen Horowitz and a Silicon Valley icon. Marc was also an early pioneer of the internet, and at the age of 22 built Mosaic, which was the first widely adopted web browser. We cover how software is making the world better, how slow sectors like education, healthcare, and housing are eating the economy, and Marc’s vision for the future of A16Z.
06.28.2021