Joys of Compounding
Episode 15 Biotech’s Chief Evangelist
Joys of Compounding

Episode 15: Biotech’s Chief Evangelist

Joys of Compounding

Episode 15

Biotech’s Chief Evangelist

John Crowley is the CEO of the Biotechnology Innovation Organization. We cover the inspirational story of his search to find a cure for the deadly Pompe disease, what he learned about leadership by serving in the military, and what every investor should know about biotech.

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(00:00:00) - Welcome to the Art of Investing

(00:05:09) - First Question - The Young John Crowley 

(00:09:53) - An Educational Odyssey - Naval Academy to Harvard

(00:12:40) - Embracing Challenges and Pivots in Life

(00:16:00) - The Crowley's Battle with Pompe Disease

(00:23:59) - The Biotech Industry's Evolution at the Turn of the Century

(00:26:02) - The Promise and Challenges of Gene Therapy

(00:30:54) - The Journey of Starting a Biotech Company: From Novozyme to Amicus

(00:32:55) - The Challenges and Triumphs of Drug Discovery and Commercialization

(00:38:12) - Advice for Aspiring Biotech Investors

(00:42:26) - The Ambitious Vision of Amicus

(00:48:10) - Acquiring New Technologies and Overcoming Financial Hurdles

(00:54:19) - John’s Personal Triumphs Amidst Professional Challenges

(01:02:08) - Megan Crowley's Journey and Family Pride

(01:14:07) - The Current State and Future of Biotechnology

(01:21:28) - The Impact of M&A in Biotech and Pharma

(01:29:11) - Leadership Lessons from the Frontlines of Biotech

(01:34:32) - Balancing Life, Duty, and Passion

(01:36:09) - Reflecting on Legacy and Purpose

 

Biotech’s Chief Evangelist

Introduction

Rick
Our teacher today is John Crowley, the man Tim Ferriss referred to as the real-life Captain America. The fact is it's difficult to appropriately describe John and the Crowley family story without drawing comparisons to superheroes. Harrison Ford give it a shot, and the result is Extraordinary Measures. A blockbuster movie, he starred in alongside Brendan Fraser and Keri Russell, which is based on Geena Anand's book "The Cure" about John and his wife's journey to save two of their children from a then untreatable disease called Pompe.

Thanks to John, that's no longer the case. And now more than 20 years later, both of his children and many others with Pompe are not only still living, but they are thriving as a source of inspiration for others battling rare diseases. Since that time, John has gone on to build several successful biotech companies, including Amicus Therapeutics, where he currently serves as the Executive Chairman. On in his free time and in response to 9/11, John decided to enlist as a commissioned officer in the U.S. Navy Reserve, where he served from 2005 to 2016 in the global war on terrorism, with service in Afghanistan and assignments alongside the Joint Special Operations Command or JSOC; the Naval Special Warfare Development Group and the CIA.

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